WorkingNotes
WorkingNotes
Working notes on modeling human skeletal muscle processes during exercise
The main task before us is incredibly complex and cannot be fully resolved at this time. But an interesting challenge must be a little crazy.
The working notes: The model development roadmap.
The amount of data available to date, compared to the outstanding issues, suggests that a fairly complete model will be at least 90% hypothetical. Such a model cannot be truly validated. Its adequacy can only be confirmed by the general behaviour of the known variables.
The summary diagram of some data problems for modeling.
The diagram of protein localization data problems.
Localization_of_proteins_in_the_cytoplasm_of_myocytes.png
The working notes: AMPK localization, questions.
AMPK_localization,_questions.pdf
The working notes: Data for fitting, problems, Different pH dynamics in MRS studies and when measuring pH using biopsy, different La dynamics.
