WorkingNotes

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WorkingNotes

Working notes on modeling human skeletal muscle processes during exercise

The main task before us is incredibly complex and cannot be fully resolved at this time. But an interesting challenge must be a little crazy.


The working notes: The model development roadmap.

Model_development_roadmap.pdf

The amount of data available to date, compared to the outstanding issues, suggests that a fairly complete model could be at least 90% hypotheses because it cannot be truly validated.


The summary diagram of data problems for modeling.

Data_problems.png


The diagram of protein localization data problems.

Localization_of_proteins_in_the_cytoplasm_of_myocytes.png


The working notes: AMPK localization, questions.

AMPK_localization,_questions.pdf


The working notes: Data for fitting, problems, Different pH dynamics in MRS studies and when measuring pH using biopsy, different La dynamics.

Data_for_fitting,_problems,_Different_pH_dynamics_in_MRS_studies_and_when_measuring_pH_using_biopsy,_different_La_dynamics.pdf