Difference between revisions of "Data availability for the manuscript"

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===Access to the model===
 
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<p align=justify> The modular model with all submodules as well as values of the model parameters in each module are available on BioUML web-server online (click [https://sirius-web.org/bioumlweb/#de=data/Collaboration%20(git)/Muscle%20metabolism/Models/Integrated%20Model%202021/ here] and use "demo" access button). The model project is presented on the left side of the workspace:</p>
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<p align=justify> The modular model with all submodules as well as values of the model parameters in each module are available on BioUML web-server online (click [https://sirius-web.org/bioumlweb/#de=data/Collaboration%20(git)/Muscle%20metabolism/Models/Integrated%20Model%202021/ here] and use "demo" access button) or can be accessed via gitlab (click [https://gitlab.sirius-web.org/virtual-patient/muscle-metabolism here]). The model project is presented on the left side of the workspace:</p>
  
  

Revision as of 17:14, 28 May 2021

Model availability and reproduction of simulation results

Access to the model

The modular model with all submodules as well as values of the model parameters in each module are available on BioUML web-server online (click here and use "demo" access button) or can be accessed via gitlab (click here). The model project is presented on the left side of the workspace:



  • Figure 1. The workspace of the model project in web-version of the BioUML platform. Two rectangles with red borders indicate the Trea area of the workspace and the corresponding place of the model project, respectively.



To open the integrated model or submodel diagram that is of interest, double click with the left mouse button on its icon in the Tree Area:



  • Figure 2.1. An integrated modular model linking metabolism, Ca2+-dependent signaling transduction and regulation of gene expression in human skeletal muscle (To consider the model in more details click on the figure).


  • Figure 2.2. A general SBGN diagram of the modular model describing metabolism in fibers I type taking into account metabolic processes in the cytoplasm, in the mitochondrion and transport reactions between two compartments (To consider the diagram in more details click on the figure).


  • Figure 2.3. SBGN diagram of the cytosol compartment in fibers I type representing all metabolic reactions and corresponding math equations in the module.

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